A genetic test requires a sample of your DNA, which is present in the cells that make up your body. A hereditary cancer specialist will select the genetic test that makes the most sense for you based on your personal and/or family history of cancer. A small amount of your blood or a saliva sample will be sent to a lab for analysis. Once a sample is received at the lab, your DNA can be isolated and examined for mutations within genes selected for testing. Your test results will indicate your inherited risk of developing cancer.
Hereditary Breast and Ovarian Cancer SyndromeBRCA1 AND BRCA2 ASSOCIATED CANCERS
Lynch SyndromeMLH1, MSH2, MSH6, PMS2, AND EPCAM ASSOCIATED CANCERS
Lynch Syndrome (LS) is caused by mutations in one of five genes: MLH1, MSH2, MSH6, PMS2, and EPCAM. Lynch Syndrome is also sometimes known as Hereditary Non-Polyposis Colorectal Cancer (HNPCC). People with LS have a higher risk of developing several different types of cancer. The highest risks are for colorectal cancer in men and for endometrial cancer in women. Some people with Lynch Syndrome may be diagnosed with cancer two or more times in their lifetime.